Media makes a difference
A simple subject, such as a dog profile can change significantly, depending on the art media used to express the subject. For me the media often sets the tone of the feeling being created in the picture. How you express with different tools is some thing to keep in mind when working on a subject.
With pen and ink detail and design sing out. Ink and a summi brush will be loose and free spirited. When using acrylic color and texture dominate. But then if the paint is watercolor the mood and color will create a totally different style. This is why I love to try new media, just to see what the media has to teach me. There is something to learn from every tool we try.